Endocrine Abstracts

Introduction: Inconsistent data exist as to whether menopause is associated with increased cardiovascular disease (CVD) risk. However, few studies have evaluated differences in apolipoprotein metabolism according to menopausal status and gender. The aim of this study was to investigate the effects of gender and menopause on serum apolipoprotein B (apoB), A-I (apoA-I) and A-II (apoA-II) concentrations.Methods/design: A cross-sectional analysis was underta...

Background: Increased adiposity is associated with increased cardiovascular disease (CVD) risk but among overweight individuals clarification is needed of relationships between insulin sensitivity, fat distribution and metabolic health that might contribute to this risk.Methods: During the Heart Disease and Diabetes Research Indicators in a Screened Cohort (HDDRISC) study, 560 employment cohort normoglycaemic (FPG less than 7...

Background: Increased adiposity is associated with increased cardiovascular disease (CVD) risk but among overweight individuals clarification is needed of relationships between insulin sensitivity, fat distribution and metabolic health that might contribute to this risk.Methods: During the Heart Disease and Diabetes Research Indicators in a Screened Cohort (HDDRISC) study, 560 employment cohort normoglycaemic (FPG less than 7...

Introduction: Data on the effect of hormone replacement therapy (HRT) and tibolone on lipoprotein(a) (Lp(a)), an independent risk factor for cardiovascular disease, are heterogeneous and conflicting. The aim of this study was to investigate the effect of HRT and tibolone on Lp(a) concentrations in post-menopausal women.Methods/design: MEDLINE, Scopus, EMBASE and Cochrane databases were searched (up to February 2016). Two researchers identified randomized...

Objective: Menopausal transition has been associated with an increased risk of cardiovascular disease (CVD), mainly attributed to atherogenic dyslipidaemia, central obesity and insulin resistance. Whether arterial hypertension (AH) also contributes to menopause-associated CVD is currently unknown. The aim of this study was to systematically investigate and meta-analyze the best available evidence regarding the association between early menopause (EM) and AH risk.<p class="...